Developmental Biology & Genetics Graduate Training Program
The Developmental Biology
& Genetics track emphasizes research training in molecular and genetic
aspects of cellular and developmental biology. The faculty use a variety of
experimental systems including yeast, hydra, fruit flies, amphibians, chick,
mouse, and human, and they use broad-based approaches to study many important
problems including embryonic induction, pattern formation, growth control,
regeneration, neurogenesis, tumorigenesis, signal transduction, and metabolic
regulation. By combining diverse groups of researchers linked by shared
interests in biology within a single track, we hope to expose students to a
broad range of influences from and intellectual interactions with the various
faculty members. The number of professors involved with the track increases the
resources available as students receive training in some of the most active and
rapidly growing research areas in biology.
Developmental Biology & Genetics is Appropriate for Students Interested In:
Functional genomics
Developmental genetics
Human genetics
Developmental biology
Neurobiology
Requirements
Students
in the Genetics and Development Biology track are required to take four core courses
(MB203, MB204, DB231B and MB206) plus a course in genetics (DB210 or MBB207),
followed by two additional courses chosen as electives (e.g., DB231C, MBB212,
P&B210).
First year graduate students
rotate through three laboratories in order to experience research activities
and to aid them in selection of a dissertation advisor by the end of their
first year. In addition to the formal courses, all graduate students are
expected to participate in the weekly Developmental Biology and Genetics Journal
Clubs, and the Departmental Seminar series.
Electives
Chromatin Structure and Function (BC225) - http://www.healthaffairs.uci.edu/biochem/resources/bc225.html
Developmental Biology & Genetics Faculty
Track coordinator - Rahul Warrior, +
Bogi Andersen,
+
Ph.D., Assistant Professor of Medicine and Biologyical Chemistry
Transcriptional regulation in the developmental biology
of epidermis and mammary gland
Kavita Arora,
+
Ph.D., Assistant Professor of Developmental & Cell Biology
Drosophila development; TGF-b signal transduction; cell signaling
Lee Bardwell, +
Ph.D., Assistant Professor of Development & Cell Biology
Intracellular signalling in development and disease
Bruce Blumberg, +
Ph.D., Assistant Professor of Development & Cell Biology
Gene regulation by nuclear hormone receptors in
vertebrate development and adult physiology
Peter J. Bryant,
+
Ph.D., Professor of Developmental & Cell Biology
Molecular controls on cell proliferation in Drosophila
Susan V. Bryant, +
Ph.D., Professor of Developmental & Cell Biology
Molecular basis of limb development and regeneration
Anne L. Calof, +
Ph.D., Professor of Anatomy & Neurobiology and Developmental & Cell
Biology
Molecular regulation of cell number in the developing and
regenerating nervous system
Ken W.-Y. Cho, + Ph.D.,
Assistant Professor of Developmental & Cell Biology
Growth factor signaling and functional genomics in
Xenopus and zebrafish
Xing Dai, + Ph.D.,
Assistant Professor of Biological Chemistry
Role of the regulatory proteins Ovo in germ cell and
epidermal differentiation
J. Jay Gargus,
+
M.D./Ph.D., Professor of Physiology & Biophysics and Pediatrics
Genetic diseases of cell signaling
Steven Gross, +
Ph.D., Assistant Professor of Developmental & Cell Biology
Laser tweezers; in vivo study of molecular motors
Lan Huang, +
Ph.D., Assistant Professor of Physiology & Biophysics and Development &
Cell Biology
Proteomics/mass spectrometry, signaling networks,
posttranslational modifications, biomarkers in cancer
Taosheng Huang, +
M.D./Ph.D., Assistant Professor of Pediatrics and Developmental & Cell
Biology
Molecular basis of genetic diseases in humans
Peter Kaiser
+,
Ph.D., Assistant Professor of Biological Chemistry
Cell cycle control; regulation of proteins by
ubiquitination
Arthur D. Lander,
+
M.D., Ph.D., Professor of Developmental & Cell Biology and Pharmacology
Mechanisms of growth factor action; extracellular matrix;
developmental neurobiology
Eva Y.-H. P.
Lee, +
Ph.D., Professor of Biological Chemistry and Developmental & Cell Biology
Cell cycle checkpoint pathways and molecular genetic
studies of breast cancer using mouse models
Haoping Liu,
+
Ph.D., Assistant Professor of Biological Chemistry
MAP kinase mediated signal transduction in yeast
Ulrike
Luderer, + Ph.D., Assistant Professor of
Medicine, Occupational & Environmental Medicine and Developmental &
Cell Biology
Roles of glutathione in ovarian follicular development
and in pre-implantation embryonic survival
Grant MacGregor,
+
Ph.D., Assistant Professor of Developmental Biology
Gametogenesis in the mouse
J. Lawrence Marsh, +
Ph.D., Professor of Developmental & Cell Biology
Regulation of growth factor signaling in patterning,
regeneration and oncogenesis
Edwin
S. Monuki, + M.D./Ph.D., Assistant Professor of
Pathology and Developmental Biology
Cerebral cortex development and disease
Robert K. Moyzis,
+
Ph.D., Professor of Biological Chemistry
Human genome project and complex genetic disease
Diane K. O'Dowd, +
Ph.D., Professor of Developmental & Cell Biology and Anatomy &
Neurobiology
Regulation of electrical excitability and synaptic
connectivity in the central nervous system of mammals and invertebrates
Maike Sander,
+
M.D., Assistant Professor of Developmental & Cell Biology
Transcriptional control of CNS and pancreas development
in mice
Suzanne B.
Sandmeyer, + Ph.D., Professor of Biological
Chemistry and Microbiology & Molecular Genetics
Molecular genetics of retroviruses and stress-induced
genes in yeast
Tom Schilling, +
Assistant Professor of Developmental & Cell Biology
Skeletal and neural patterning; mutational analysis and
molecular genetics in the zebrafish
Robert E. Steele,
+
Ph.D., Associate Professor of Biological Chemistry
Molecular biology of Hydra development
Leslie M.
Thompson, + Ph.D. Assistant Professor of
Psychiatry and Biological Chemistry
Molecular and biochemical mechanisms of disease
pathogenesis and therapeutic approaches to human neurodegenerative disease
Paul Vrana, +
Ph.D., Assistant Professor of Biological Chemistry
Mechanism of genomic imprinting in deer mice
Doug
Wallace, + Ph.D., Professor of Biological
Chemistry and Ecology & Evolutionary Biology
Human mitochondrial genetics and molecular medicine
Rahul Warrior, +
Ph.D., Assistant Professor of Developmental & Cell Biology
Nuclear migration in development and disease;
Transcriptional response to growth factor signaling
G-protein signal transduction; cell
polarization; Systems Biology.
Kyoko
Yokomori, + Ph.D., Assistant Professor of
Biological Chemistry
Molecular mechanisms of chromosome dynamics and gene
regulation
For more information, please see the Developmental Biology Web Page