Graduate Program in Molecular Biology, Genetics & Biochemistry
Faculty research areas include:
Biomedical Informatics
Cancer Biology
Cell Biology
Developmental Biology & Genetics
Experimental
Pathology
Immunology & Pathogenesis
Infectious
Diseases
Mechanisms of Gene Expression
Molecular Neurobiology
Structural Biology &
Molecular Biophysics
Virology
Faculty in the Molecular Biology, Genetics & Biochemistry Program
Bogi Andersen,
+
Transcriptional regulation in the developmental biology of epidermis and
mammary gland
Aileen J. Anderson,
+
Inflammation and immune response mechanisms in CNS injury; mechanisms of
functional recovery after spinal cord injury
Hoda Anton-Culver,
+
Cancer and genetic epidemiology, statistical and molecular genetics, medical
informatics
Ruslan
Aphasizhev, + Molecular biology of trypanosome RNA editing
and template-independent nucleotide recognition and transfer
Kavita Arora,
+
Drosophila development; TGF-b signal
transduction; cell signaling
Dana
W. Aswad, + Regulation of protein function by
covalent modification
Kenneth M. Baldwin,
+
Activity and hormonal factors regulating striated muscle plasticity
Tallie Z. Baram, +
Excitotoxicity and epilepsy; neurobiology of stress; neuropeptide
neuromodulation
Alan
G. Barbour, + Molecular pathogenesis and
immunology of vector-borne infections
Lee Bardwell, +
Intracellular signalling in development and disease
Hans
Ulrich Bernard, + Gene expression of
papillomaviruses; progression of cervical cancer
Michael W. Berns, +
Laser microsurgery of cells, embryos, and tissues
Bruce Blumberg, +
Gene regulation by nuclear hormone receptors in vertebrate development and
adult physiology
Hans R. Bode,
+
Pattern formation and stem cell differentiation
Emiliana
Borrelli, + Dopaminergic system, with
particular focus on dopamine D2 receptors
Carrie B. Brachmann, +
Spatial regulation of developmental apoptosis; Bcl-2 proteins; cell signaling
Ralph A. Bradshaw,
+
Growth factor action; signal transduction; protein processing
Peter J. Bryant,
+
Tumor-suppressor genes of Drosophila and humans
Susan V. Bryant, +
Molecular basis of limb development and regeneration
Michael J. Buchmeier, Viral biology and pathogenesis, structural and functional
proteomics of viruses, and biodefense related pathobiology
Michael D. Cahalan, + Ion channels in the nervous and immune systems
Vincent Caiozzo,
+ Skeletal muscle adaptation, sarcomeric
proteins, contractile properties, rehabilitation
Anne L. Calof, +
Molecular mechanisms of neurogenesis, neuronal differentiation, and cell death
David
Camerini, + Pathogenesis and molecular biology
of HIV-1
Paolo Casali,+ Human immune response to cancer and viral diseases
Jefferson Y.
Chan, +
Regulation of genes associated with oxidative stress
K. George Chandy,
+
Molecular biology and structure of ion channels; novel therapeutic agents
Phang Lang Chen,+ Critical role of tumor suppressor genes in
the genesis and progression of cancer
Ken W.-Y. Cho,
+
Molecular mechanisms of axis specification in Xenopus
Olivier
Civelli, + Molecular neurobiology, G
protein-coupled receptors, peptide neurotransmitters
Melanie
Cocco, +
NMR spectroscopy, DNA-binding proteins, membrane proteins, cancer
Xing Dai, + Role
of the regulatory proteins Ovo in germ cell and epidermal differentiation
Luis de la Maza, + Vaccines for Chlamydia trachomatis.
Michael Demetriou, + Molecular biology and glycobiology of T cell dysfunction in autoimmune demyelinating disease
Peter Donovan,
+ Molecular genetics of
germ cell and stem cell development
Aimee Edinger, + Apoptosis, cancer, intracellular trafficking
Robert Edwards, + Development of colitis and colon cancer using a G-protein mouse model of inflammatory bowel disease
Hung
Fan, +
Molecular biology and pathogenesis of mouse and human retroviruses
Mark J. Fisher, +
Mechanisms of cerebrovascular stroke
David
A. Fruman, + Signal transduction in lymphocytes
Christine M. Gall, +
Neuroplasticity, chemical neuroanatomy, and neurotrophic factors
J.
Jay Gargus, + Molecular analysis of membrane
signaling proteins
Paul
Gershon, + mRNA transcription and modification
Roland
A. Giolli, + Subcortical visual system and
oculomotor control system
Charles
G. Glabe, + Amyloid Ab peptide in Alzheimer's pathogenesis; gamete recognition
Alan
L. Goldin, + Molecular analysis of ion channel
function
Celia
Goulding, + Structural and biochemical
studies of molecular assemblies in Mycobacterium
tuberculosis
Steven Gross, +
Laser tweezers; in vivo study of molecular motors
Ranjan Gupta, +
Peripheral nerve injury
Harry
T. Haigler, + Growth factor signal transduction;
annexin calcium-binding proteins
James E. Hall, +
Biophysics of membrane channels
Klemens Hertel, + Regulation of gene expression by alternative splicing
Todd Holmes, + Human neurodegenerative disease mechanisms in transgenic animals
Lan Huang,
+
Proteomics/mass spectrometry, signaling networks, posttranslational
modifications, biomarkers in cancer
Taosheng Huang, +
Molecular basis of genetic diseases in human
Christopher
C.W. Hughes, + Endothelial cells as initiators and
targets of immune responses
Anthony
A. James, + Malaria parasite development;
genetic manipulation of insect vectors
Frances A. Jurnak, +
Macromolecular crystallography of biological systems
Peter Kaiser
+,
Cell cycle control; regulation of proteins by ubiquitination
Hans Keirstead, +
Mechanisms of axon growth and recovery from injury
Leonard M. Kitzes, +
Auditory system neurobiology
John
J. Krolewski, + Cell signaling mechanisms
regulating proliferation and apoptosis
Arthur D. Lander,
+
Mechanisms of growth factor action; extracellular matrix; developmental
neurobiology
Thomas
Lane, +
Viral immunology
Janos K. Lanyi,
+
Structure and function in bacterial rhodopsins
Eva Y.-H. P. Lee,
+
Cell cycle checkpoint pathways and molecular genetic studies of breast cancer
using mouse models
Wen-Hwa Lee,+
Tumor-suppressor genes and why the repair mechanisms for DNA can fail and cause
subsequent accumulations of cancer-promoting mutations
Robert Leonard,+ Clinical anatomy education
Leonid
Lerner, + Pathogenesis
and therapeutic strategies for management of degenerative and age related
diseases affecting vision
Frances M. Leslie,
+
Pharmacology of drugs of abuse and developmental neuropharmacology
Steven M. Lipkin,
+ Genetics
and genomics of cancer and infertility; Molecular mechanisms of DNA mismatch
repair
Haoping Liu, + MAP
kinase signal transduction; dimorphic regulation in yeast
Ulrike
Luderer, + Regulation of glutathione synthesis
and its roles in ovarian follicular development
Hartmut
"Hudel" Luecke, + Biochemistry and macromolecular
crystallography of membrane proteins
Ray
Luo, +
Computational biology, protein structure prediction and folding mechanisms,
protein-protein interactions
David
Lyon, +
Relating fine scale circuitry to visual perception in the mammalian visual
cortex and thalamus
Grant MacGregor,
+
Gametogenesis in the mouse
J. Lawrence Marsh, +
Molecular genetics of development in Drosophila and humans
Rachel
Martin, + Solid state NMR, protein
structure, membrane proteins, physical chemistry, chemical biology
Alexander
McPherson, + Molecular structure of biological
materials
Dan Mercola,
+ Translational
research in prostatic cancer
Ronald L.
Meyer, +
Development of nerve connections, nerve injury and regeneration
Frank Meyskens,
+
Effects of oxidative stress on gene expression; cancer chemoprevention
Edwin
S. Monuki, + Cerebral cortex development and
disease
Naomi
Morrissette,+ Genetic, cell biological and
structure-function studies of tubulin and microbutules in Apicomplexan parasites
Robert K. Moyzis,
+
Human genome project and complex genetic disease
R.
Michael Mulligan, + RNA editing in plant mitochondria
and chloroplast
Edward
L. Nelson, + Tumor immunology, dendritic cell
biology, and anti-tumor immunotherapeutics
Diane K. O'Dowd, +
Electrical excitability and synaptic connectivity during development
Timothy
F. Osborne, + Transcriptional regulation of
cholesterol biosynthesis
Andre
Ouellette, + Mechanisms of innate immunity in
the mammalian intestinal epithelium
Daniele
Piomelli, +
Thomas
L. Poulos, + Protein engineering and
crystallography
Charles E. Ribak, +
Neuroplastic changes and neural circuits in epileptic brains
Markus
Ribbe,+
Fundamental biochemical processes in microbial systems
Richard
T. Robertson, + Mechanisms of axonal target
selection in developing cerebral cortex
W.
Edward Robinson, + Lentivirus (HIV and SIV)
integration, replication, and pathogenesis
Ingrid K. Ruf, + Molecular mechanisms of Epstein-Barr Virus latency and pathogenesis
Maike
Sander, +
Transcriptional control of CNS and pancreas development in mice
Suzanne B.
Sandmeyer, + Molecular genetics of a
position-specific yeast retrovirus-like element
Rozanne
M. Sandri-Goldin, + Regulatory functions of a
post-transcriptionally acting herpes virus protein
Paolo
Sassone-Corsi, + Mechanisms of signal transduction able
to modulate nuclear functions and, in particular gene expression, chromatin
remodeling and epigenetic control
Tom Schilling, +
Skeletal and neural patterning; mutational analysis and molecular genetics in
the zebrafish
Steven Schreiber,+
Mechanisms of neural degeneration in brain and spinal cord
Michael E.
Selsted, + Host defense systems in phagocytic
leukocytes and mucosal epithelium
Bert
L. Semler, + Replication of picornavirus RNAs;
RNA-protein and protein-protein interactions
Donald
F. Senear, + Interactions of proteins and DNA in
transcriptional regulation
Martin A. Smith, +
Synaptogenesis: regulation of gene expression and RNA splicing
Ivan Soltesz, +
Function and modulation of synaptic GABAA
receptor
Eric
J. Stanbridge, + Tumor suppressor genes and
oncogenes in human cancer
Robert E. Steele,
+
Molecular biology of Hydra development
Oswald Steward, +
Genes that affect cellular responses to CNS injury
Christine
Suetterlin,+ Golgi dynamics during mitosis, sumoylation
Ming
Tan, +
Gene expression and pathogenesis in Chlamydia trachomatis
Andrea
J. Tenner, + Molecular basis of modulation of
human leukocyte function; Alzheimer's disease
Leslie M.
Thompson, + Molecular and biochemical
mechanisms of disease pathogenesis and therapeutic approaches to human
neurodegenerative disease
Sheryl
Tsai, +
Drug design and crystallography of protein complexes
Larry E. Vickery,
+
Molecular chaperones and protein folding
Luis P. Villarreal,
+
Tissue-specific viral and cellular gene expression; viral vectors
Paul Vrana, +
Mechanism of genomic imprinting in deer mice
Doug
Wallace, + Human mitochondrial genetics and
molecular medicine
Craig
Walsh, +
Apoptotic mechanisms in immune development and homeostasis
Ping
Wang, +
Molecular hormone actions in the normal and diseased heart
Rahul Warrior, +
Nuclear migration in development and disease; Transcriptional response to
growth factor signaling
Marian
L. Waterman, + Regulation of gene expression in
development and cancer
Steven L. Wechsler, + Herpes simplex virus latency, reactivation and recurrent disease
Gregory
Weiss, +
Bioorganic chemistry, chemical biology, protein engineering, molecular biology
and biochemistry
John H. Weiss, +
Mechanisms of neurodegeneration - in vitro study
Stephen H. White, + Protein
folding in membranes
Tau-Mu Yi, + G-protein signal
transduction; cell polarization; Systems Biology.
Kyoko Yokomori,
+
Gene expression and chromatin structure
Fan-Gang Zeng, +
Auditory processing; speech perception; neural prostheses