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Current Seminars & Events

Molecular Biology and Biochemistry (MB&B)

12:00 PM Friday 25 May Stephen Beverley
The intersec/on of RNA interference, dsRNA viruses and Leishmania virulence
 
 

Prior MB&B Seminars & Events


12:00 PM Friday 11 May Brendan Manning
Connecting cancer to metabolism through a nutrient sensing signaling network
12:00 PM Friday 27 April Russ Hille
The Structural Basis of Catalytic Power in Xanthine Oxidase and Related Enzymes
12:00 PM Friday 13 April Jack Johnson
Maturation of dsDNA Viruses: insights into elegantly programmed nanomachines
12:00 PM Friday 23 March Stephen Lippard
Understanding and Improving Platinum Anticancer Drugs
12:00 PM Friday 02 March William Sullivan
An integrated stress response mediates microbial latency in parasitic protozoa
12:00 PM Friday 17 February Dmitry Loukinov
CTCF and its testis specific paralog BORIS in shaping of epigenome in cancer
12:00 PM Friday 20 January Jianke Zhang
Apoptosis and necrosis in embryos and lymphocytes.
12:00 PM Friday 09 December Celia Goulding
Structural Insights Into Mechanisms of Bacterial Survival
12:00 PM Friday 02 December Seth Rubin
Molecular Mechanisms Regulating the Retinoblastoma Tumor Suppressor Protein
12:00 PM Friday 04 November Markus Ribbe
Novel Catalytic Features of Nitrogenase Homologues
12:00 PM Friday 21 October Paul Oh
Mechanism and Therapy for a Vascular Anomaly
12:00 PM Friday 30 September Michael Brown
Frustration and dynamics in biomembrane function viewed by molecular spectroscopy
12:00 PM Monday 13 June Philip Thorpe
Targeting Tumor Vasculature and Reactivating Tumor Immunity with bavituximab: Preclinical and Clinical Studies
12:00 PM Friday 27 May Andrew Thorburn
Autophagy and Cancer Therapy
12:00 PM Friday 13 May Irene Nga Wing Lee
A chemical approach to study mitochondrial ATP-dependent proteases
12:00 PM Friday 29 April Louis Weiner
New Approaches to Antibody-Based Cancer Therapy
12:00 PM Friday 15 April Jon Boyle
Combining genetics and genomics to identify virulence genes in Toxoplasma gondii
12:00 PM Friday 01 April Thomas Bernhardt
Control of cytokinetic ring assembly by a chromosome-associated regulator of bacterial tubulin polymerization
11:00 AM Thursday 24 March Nenad Ban
The next frontiers in ribosome research
4:00 PM Tuesday 22 March Jean-Luc Popot
Applications of amphipols to membrane protein studies
12:00 PM Friday 11 March Harald Neumann
Microglial ITAM/ITIM signaling receptors in microglia-neuron interactions
10:00 AM Friday 04 March Lee Ligon
Tubulin Post-Translational Modifications: Road Signs in the Cell?
10:00 AM Thursday 03 March Jennifer Prescher
Lighting up life with chemical tools and noninvasive imaging
10:00 AM Friday 25 February Young Jik Kwon
Taming nature for cure: Semi-synthetic, synthetic, and chimeric viral particles for tunable and synergistic gene therapy
12:00 PM Wednesday 23 February Kazuyuki Tatsumi
New Synthetic Routes to Fe-S Clusters Relevant to the Active Sites of Nitrogenase
12:00 PM Friday 18 February Vadim Cherezov
Structure and Function of G Protein-Coupled Receptors
12:00 PM Friday 04 February Joanie Hevel
Unraveling how Protein Arginine Methyltransferase I (PRMT1) adds to the complexity of our proteome
10:00 AM Friday 28 January Alex Loukas
Vaccines against blood-feeding human helminths
12:00 PM Friday 21 January Eric Baehrecke
Eating on the fly: function of autophagy in cell survival and death
12:00 PM Friday 03 December Domagoj Vucic
Ubiquitin ligases c-IAP1/2 are critical regulators of TNF family signaling and targets for therapeutic intervention in tumors
12:00 PM Friday 05 November Brant Weinstein
Novel regulators of angiogenesis and lymphangiogenesis - new insights from the zebrafish
12:00 PM Friday 23 July Yu-Jui Yvonne Wan
Retinoid-mediated Signaling in Liver Health and Disease
12:00 PM Friday 14 May Felipe Sierra
Aging Biology: current status and prospects
11:00 AM Wednesday 05 May Blake Hill
Getting Mitochondria in Shape through Protein Amphitropism: A Lethal Mutation in the Mechanoenzyme Drp1 affects its Recruitment and Assembly
12:00 PM Friday 30 April Jordan Pober
Human T Cell Interactions with Vascular Cells
12:00 PM Friday 16 April J.P. Ma
Improving X-ray Structures of Supramolecular Complexes and Membrane Proteins at Lower Resolution Limit
12:00 PM Friday 02 April John H. Golbeck
Wiring Photosystem 1 for Solar Biofuel Production
12:00 PM Friday 12 March Eileen Jaffe
Morpheeins--a new view of qauternary structure dynamics and allosteric drug action
12:00 PM Friday 26 February James Chen
Chemical probes of embryonic development
12:00 AM Friday 12 February Jeffrey Miller
Accelerated Evolution of Host-Parasite Interactions by Diversity-Generating Retroelements
12:00 PM Friday 29 January John Peters
Insights into the biosynthesis and evolution of the complex iron-sulfur clusters containing hydrogenase and nitrogenase
12:00 PM Friday 15 January Joel Gottesfeld
Development of histone deacetylase inhibitors as therapeutics for neurodegenerative diseases
12:00 PM Monday 03 August Jurgen Moser
ATP-Driven Reduction of Dark-Operative Protochlorophyllide Oxidoreductase Resembles Nitrogenase Catalysis
12:00 PM Friday 05 June Adrian Ferre-D'Amare
Catalysis and gene regulation by RNA: unexpected sophistication by a simple biopolymer
12:00 PM Friday 24 April Akif Tezcan
Inorganic Control of Biological Self-Assembly
12:00 PM Friday 03 April Kun-Liang Guan
The TSC-mTOR and Hippo pathways in cell growth and cancer
12:00 PM Friday 06 March James Bowie
What drives membrane protein folding?
12:00 PM Friday 20 February David Cheresh
Unexpected role of VEGF in the tumor microenvironment: New insights into cancer therapy
12:00 PM Friday 09 January Joseph Jez
Sensing Cellular Environment Through Molecular Switches in Thiol Metabolism
12:00 PM Friday 05 December Yong Duan
Simulation of protein folding and dynamics by physics-based all-atom models
12:00 PM Friday 07 November Vahe Bandarian
Chemical Biology of Secondary Metabolism
12:00 PM Friday 24 October Anthony Kossiakoff
Synthetic antibodies derived from a minimalized genetic code: New applications for structural and cell biology
12:00 PM Friday 10 October Anthony Berdis
Developing Novel Therapeutic Agents by Exploiting Pro-Mutagenic DNA Synthesis
12:00 PM Friday 26 September Mischa Machius
Alpha-Ketoacid Dehydrognease: Structure, Mechanism, and Regulation of a 9 Mega-Dalton Multi-Enzyme Machine
12:00 PM Friday 06 June Squire Booker
Taking a Hit: Self-Sacrifice as a Strategy in the Biosynthesis of Lipoic Acid
12:00 PM Friday 23 May Jeremy Boss
Transcription Regulation of Immune System Genes
12:00 PM Friday 09 May J. Martin Bollinger, Jr.
Formation and function of a radical-initiating manganese/iron cofactor in the ribonucleotide reductase from Chlamydia trachomatis
12:00 PM Friday 25 April Carsten Krebs
Mechanism of Oxygen Activation by Mononuclear Non-Heme Enzymes
3:00 PM Monday 14 April Janice Pata
Snapshots of an Error-Prone Polymerase Making a Single-Base Deletion Mutation
12:00 PM Friday 11 April Reuben Shaw
The LKB1 kinase: tumor suppressor and key regulator of AMPK and metabolism
12:00 PM Friday 14 March Adam Martiny
Patterns and Implications of Gene Gain and Loss in the Evolution of Prochlorococcus
12:00 PM Friday 29 February Jean-Luc Popot
Developing the applications of amphipols to membrane protein studies. An update.
12:00 PM Friday 15 February Michael Gilson
Entropy, Affinity and the Design of Targeted Molecules
12:00 PM Friday 01 February Joseph Jarrett
Iron-sulfur Clusters as Sulfur Donors in Cofactor Biosynthesis
12:00 PM Friday 18 January Andrej Luptak
Mammalian Ribozymes
4:00 PM Tuesday 11 December David Camerini
HIV Pathogenesis and Immunity
12:00 PM Friday 30 November Joyce Bishoff
Tissue Vascularization using Blood-derived and Bone Marrow-derived Progenitor Cells. An abstract is below.
12:00 PM Friday 09 November Brian V. Geisbrecht
Structural Biology as a Tool for Understanding Immune Evasion by Staphylococcus Aureus
12:00 PM Friday 26 October Peter Girguis
Peering into the private lives of microbes: insight into the ecological physiology of deep sea microbes using conventional and novel approaches
12:00 PM Friday 12 October Anand K. Ganesan
Genome wide RNAi Identifies Pharmaceutically Tractable Regulators of Melanin Production
12:00 PM Friday 28 September Wei Yang
Problem Oriented Sampling Design to Quantitatively Understand Biomolecular Recognitions and Enzymatic Reactions
12:00 PM Friday 14 September Jae Bum Kim
Lipid Dysregulation and Metabolic Disorders
12:00 PM Thursday 26 April Ralf Mendel
Molybdenum metabolism in plants and humans and its crosstalk to FeS and Cu metabolism
12:00 PM Friday 20 April Benjamin Segal
Th17 cells in experimental autoimmune encephalomyelitis and multiple sclerosis: Are they the genuine pathogenic effectors in autoimmune inflammation?
12:00 PM Friday 06 April Coran Watanabe
Inspiration from Nature: Natural Products in Drug Discovery Efforts
12:00 AM Friday 23 March
MB&B Research Retreat
12:00 PM Friday 23 February P.R. Lowenstein
The microanatomy of brain immune responses: immunlogical synapses in the brain
12:00 PM Tuesday 06 February Janice Yoshizawa, Jason Stagno
Research in Progress (RIP)
12:00 PM Tuesday 12 December Ray Luo
Computational studies of p53 cancer mutations
12:00 PM Tuesday 05 December Craig Walsh
Research in Progress (RIP)
12:00 PM Tuesday 28 November Markus Ribbe
Research in Progress (RIP)
1:30 PM Tuesday 28 November Amber Donahue
The Role of Phosphoinositide 3-Kinase in the Development and Activation of B Lymphocytes
10:00 AM Tuesday 07 November Stephanie Ramos
Regulation of Autoimmunity by DRAK2
12:00 PM Tuesday 07 November Silvia Delker, Ahmend Al-Qahtani
Research in Progress (RIP)
12:00 PM Tuesday 31 October Rahasson Ager, John Coroneus
Research in Progress (RIP)
12:00 PM Friday 27 October Kevin MacKenzie
Spacificity of helix-helix interactions in membranes and detergents
12:00 PM Tuesday 24 October Novelle Kimmich, Jennifer Houman
Research in Progress (RIP)
12:00 PM Tuesday 17 October Amanda Laust, Tyler Korman
Research in Progress (RIP)
12:00 PM Tuesday 10 October Jessica Schulz, Cathie Overstreet
Research in Progress (RIP)
12:00 PM Friday 29 September Rainer Reinscheid
Neuropeptide S Receptor: From Point-Mutations to Human Psychiatric Disorders
12:00 PM Friday 26 May Michela Plateroti
Cross-talk between the thyroid hormone and the Wnt signalling pathways in the control of intestinal epithelial progenitors proliferation
12:00 PM Friday 21 April Anne Brunet
FOXO transcription factors in the control of longevity
12:00 PM Friday 03 March Xinhua Ji
The Mechanism of Double-Stranded RNA Processing by Ribonuclease III: How Dicer Dices
12:00 PM Friday 10 June Mike Flanagan
Fragment-based drug discovery: From cytokines to kinases
12:00 PM Friday 13 May Gabriel Fenteany
Chemical Approaches to Understanding Cell Migration
12:00 AM Friday 01 April Mark Mamula
Using Protein Chemistry to Trigger Autoimmune Responses to Tumors
12:00 AM Friday 18 March David Namazee
Receptor editing and B cell tolerance
12:00 AM Friday 04 March Kees Murre
Regulation and function of helix-loop-helix proteins in stem cell homeostasis and lymphocyte development
12:00 AM Friday 04 March Cornelius Murre
The regulation and function of helix-loop-helix proteins in hematopoietic stem cells and lymphoid development
12:00 AM Friday 04 February Mattias Wabl
Genomic instability in B lymphocytes
12:00 AM Friday 21 January Mark Ginsberg
Integrin Signaling in Cancer and Immunity
12:00 PM Friday 03 December Paul Brindle
Analysis of the transcriptional coactivators CBP and p300 in vivo
2:00 PM Tuesday 23 November David Fruman
Signaling pathways and transcriptional changes that drive lymphocyte activation
12:00 PM Friday 22 October John Tesmer
Structural studies of G protein-coupled Receptor Kinases
12:00 PM Friday 08 October Amy Anderson
Targeting Biodefense Organisms: From Structures to Drugs
12:00 PM Friday 24 September Susan Neuhausen
Genetic variants in IGF-pathway genes and cancer risk
11:00 AM Friday 30 July Peter Zavodszky
Structural background of the substrate specificity of Mannose-Binding Lectin Associated Serine Protease
12:00 PM Friday 04 June Ann Feeney
Many levels of control of V, D and J gene rearrangement in B lymphocytes
12:00 PM Friday 28 May Michael Lieber
Non-B DNA Structures in Physiologic and Pathologic Gene Rearrangements
12:00 PM Friday 07 May William Hahn
Cooperative interactions that transform human cells.
12:00 PM Friday 23 April Grant MacGregor
Kaposi's Sarcoma-associated Herpesvirus:
12:00 PM Friday 09 April Dean Kedes
Kaposi's Sarcoma-associated Herpesvirus: Inroads into Structure and Pathogenesis
12:00 PM Friday 05 March Yaoqi Zhou
Making a physical interaction out of statistics of protein structures.
12:00 PM Friday 20 February Steve Michnick
Towards a molocular spectrometer of the cell
12:00 PM Friday 23 January Kevin Gardner
PAS domains: A Versatile Way to Build a Biological Switch
12:00 PM Friday 09 January Alex Toker
Protein Kinase D Promotes Cellular Survival via a Novel NF-kB Signaling Pathway
12:00 PM Monday 05 January Markus Ribbe
Nitrogenases - An Intriguing Paradigm for Metallocluster Assembly
12:00 PM Monday 15 December Lisa Schechter
Going for the Gold: Mining Type-111 Secreted Effector Proteins in the Model Plant Pathogen Pseudomonas Syringae Pathovar Tomato DC3000
1:00 PM Thursday 11 December Naomi Morrissette
The Plant-Protozoan Connection: What Herbicides Tell Us About Parasite Microtubules
12:00 AM Monday 08 December Greg Somerville
Staphylococcus Aureus Physiology and Evasion of the Innate Immune Response
12:00 PM Friday 05 December Mark Bedford
The Functional Analysis of the Protein Methyltransferase, CARM1
12:00 PM Monday 01 December Anne Stellwagen
The Means to an End: Recruiting Telomerase to Native and Broken Chromosome Ends
1:00 PM Friday 14 November Lily Wu
Gene Expression-based Imaging and Therapy Targeting Prostate
12:00 PM Friday 31 October Tom Menees
RNA Branching and Debranching in the Yeast Retrovirus-like Element Ty1
12:00 PM Friday 03 October Mike Carey
Mechanisms of the Mediator Co-Activator in Pol II Transcription Complex Assembly and Function
 
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