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DTSTART;TZID=America/Los_Angeles:20261020T160000
DTEND;TZID=America/Los_Angeles:20261020T180000
DTSTAMP:20260924T172910Z
CREATED:20260810T212320Z
LAST-MODIFIED:20260924T172910Z
UID:57810-1792512000-1792519200@www.bio.uci.edu
SUMMARY:Dean’s Distinguished Lecture - Fall 2026
DESCRIPTION:Mysteries of Muscle and Movement: From Molecular Motors to Lifelong Mobility\n\n\n\nDate: Tuesday\, October 20Talk and Q&A: 4–5 p.m.Reception: 5–6 p.m.Location: Crystal Cove Auditorium\, UCI Student Center\, 311 West Peltason Drive\, Irvine \n\n\n\n\n\n\n\n\n\n\n\nThe Charlie Dunlop School of Biological Sciences at UC Irvine invites you to attend the Fall 2026 Dean’s Distinguished Lecture\, featuring Monica Daley\, Ph.D.\, director of the Center for Integrative Movement Sciences and professor in the Department of Ecology & Evolutionary Biology on October 20\, 2026\, in the Crystal Cove Auditorium at the UC Irvine Student Center. \n\n\n\n\nThis event is free and open to the public. All are welcome to attend. Food will be provided at the reception. If you have questions about this event\, please email biosci-events@uci.edu. \n\n\n\n\n\n\n\n\n\n\nAbout the Speaker:\n\n\n\n\nMonica Daley\, PhDProfessor\, Department of Ecology & Evolutionary BiologyDirector\, Center for Integrative Movement Sciences \n\n\n\n\n\nAbout Professor Daley’s Research:Most of us take for granted the ability to recover from a stumble or navigate uneven ground. Daley studies the biology that makes this possible: how muscles\, tendons\, skeletal mechanics and neural circuits work together to enable movement that is agile\, stable and economical. \n\n\n\nShow more\n\n\n\nAbout Professor Daley’s Research:Most of us take for granted the ability to recover from a stumble or navigate uneven ground. Daley studies the biology that makes this possible: how muscles\, tendons\, skeletal mechanics and neural circuits work together to enable movement that is agile\, stable and economical. Research on movement control has long centered on the brain\, but neural control acts through the physics of the body and environment. Daley’s laboratory measures what muscles do inside freely moving animals as the terrain changes underfoot. Muscle is unlike any material engineers have built\, and the models still used to describe it date to the 1920s and 1930s. Closing the gap in understanding of muscle takes a team larger than any single laboratory. Daley directs a nationwide team working across scales from molecular machinery of muscle contraction to people moving through complex environments\, with the aim to translate foundational biology into clinical and technological innovations that support lifelong mobility and health. \n\n\n\nShow less\n\n\n\n\n\nAbout Professor Daley:Monica A. Daley is Professor of Ecology and Evolutionary Biology at the University of California\, Irvine\, with joint appointments in Biomedical Engineering and Mechanical and Aerospace Engineering. \n\n\n\nShow more\n\n\n\nAbout Professor Daley:Monica A. Daley is Professor of Ecology and Evolutionary Biology at the University of California\, Irvine\, with joint appointments in Biomedical Engineering and Mechanical and Aerospace Engineering. Daley earned her B.S. in Biology at the University of Utah\, where she was inspired to become a physiologist through undergraduate research on human running and breathing. She spent a year as a research technician investigating motor control of singing in zebra finches\, which initiated a lifelong passion for understanding the interplay between muscle mechanics and neural control. She earned her Ph.D. in Organismic and Evolutionary Biology at Harvard University as a Howard Hughes Medical Institute Predoctoral Fellow\, then trained in neuromechanics and human rehabilitation as an NSF Postdoctoral Fellow at the University of Michigan. From 2008 to 2019 she was on the faculty of the Structure and Motion Laboratory at the Royal Veterinary College in London\, leading research on movement in diverse animal species. She joined UCI in 2019.Daley directs the Center for Integrative Movement Sciences\, an interdisciplinary research and training program connecting UCI scientists and students to a nationwide network of movement researchers. Her own research spans muscle physiology\, biomechanics\, sensorimotor control and bio-inspired robotics\, and she collaborates with clinicians\, engineers and roboticists. She is passionate about mentoring researchers at every career stage\, from undergraduates through faculty colleagues. Daley received the Human Frontier Science Program Young Investigator Award\, serves as a Monitoring Editor of the Journal of Experimental Biology\, and is a Fellow of the American Society of Biomechanics. \n\n\n\nShow less\n\n\n\n\n\n\n\n\n\nRegister to attend the Dean’s Distinguished Lecture\n\n\n\n\n\n\n\n\n\nIf you have questions about this event\, please email biosci-events@uci.edu.
URL:https://www.bio.uci.edu/event/deans-distinguished-lecture-fall-2026/
LOCATION:Crystal Cove Auditorium\, UCI Student Center\, A\, 311 W Peltason Dr\, Irvine\, CA\, 92697\, United States
CATEGORIES:Dean's Distinguished Lecture,Dean's Office,Events
ATTACH;FMTTYPE=image/jpeg:https://www.bio.uci.edu/wp-content/uploads/2026/09/DDL-Fall-2026.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20260415T160000
DTEND;TZID=America/Los_Angeles:20260415T180000
DTSTAMP:20260413T164327Z
CREATED:20260313T162639Z
LAST-MODIFIED:20260413T164327Z
UID:54986-1776268800-1776276000@www.bio.uci.edu
SUMMARY:Dean's Distinguished Lecture - Spring 2026
DESCRIPTION:Our Individual Differences in Navigation Ability: Building a Cognitive Profile From Brain and Behavior\n\n\n\nJoin us for a talk with Associate Professor Elizabeth Chrastil \n\n\n\n\n\n\n\nThe Charlie Dunlop School of Biological Sciences at UC Irvine invites you to attend the Spring 2026 Dean’s Distinguished Lecture\, featuring Associate Professor Elizabeth Chrastil on April 15\, 2026\, in the Crystal Cove Auditorium at the UC Irvine Student Center. \n\n\n\nNavigation is a central part of daily life. For some\, getting around is easy\, while others struggle. Some clinical populations\, such as those with Alzheimer’s disease (AD)\, display wandering behaviors and extensive disorientation. Working at the interface between immersive virtual reality and neuroimaging techniques\, my research uses these complementary approaches to inform questions about how we acquire and use spatial knowledge. In this talk\, I will discuss some of my recent work and current experiments that centers on how individuals differ in their spatial abilities\, which includes their exploration behavior and aspects of brain structure and function\, as well as sex and age. More broadly\, I will discuss how navigation lends insight into processes of human learning and memory. Further\, I will demonstrate how these techniques can be used to understand age-related changes in brain circuits and to identify those at greatest risk for AD. \n\n\n\n\n\n\nEvent Details:\n\n\n\nTalk and Q&A: 4 to 5 p.m. \n\n\n\nReception: 5 to 6 p.m. \n\n\n\n\n\n\n\n\n\n\nAbout the Speaker:\n\n\n\n\n\nElizabeth Chrastil\, PhDElizabeth Chrastil is an associate professor in the Department of Neurobiology & Behavior at the University of California\, Irvine Charlie Dunlop School of Biological Sciences. She studies how the human brain supports navigation\, spatial memory and learning — research that helps explain how people orient themselves and move through complex environments. \n\n\n\nShow more\n\n\n\nElizabeth Chrastil\, PhDElizabeth Chrastil is an associate professor in the Department of Neurobiology & Behavior at the University of California\, Irvine Charlie Dunlop School of Biological Sciences. She studies how the human brain supports navigation\, spatial memory and learning — research that helps explain how people orient themselves and move through complex environments. Chrastil leads the Spatial Neuroscience Lab\, where her team combines immersive virtual reality environments with neuroimaging techniques such as functional MRI to investigate how the brain processes self-motion and environmental cues during navigation. Her work explores how different sources of information — such as landmarks\, body motion signals and decision-making processes — contribute to building mental maps of the world and learning new spaces. She earned her PhD in cognitive science from Brown University in 2012 and joined UC Irvine after faculty and research positions at institutions including the University of California\, Santa Barbara and Boston University. Chrastil’s research broadly examines how brain systems like the hippocampus and related networks support navigation and memory\, as well as why individuals differ in their navigational abilities. \n\n\n\nShow less\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nRegister to Attend the Dean’s Distinguished Lecture\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nThis event is free and open to the public. All are welcome to attend. If you have questions about this event\, please email biosci-events@uci.edu.
URL:https://www.bio.uci.edu/event/deans-distinguished-lecture-spring-2026/
LOCATION:Crystal Cove Auditorium – UCI Student Center\, 4113 Pereira Dr.\, Irvine\, California\, 92697\, United States
CATEGORIES:Dean's Distinguished Lecture,Dean's Office,Events
ATTACH;FMTTYPE=image/jpeg:https://www.bio.uci.edu/wp-content/uploads/2026/04/Thumbnail-DDL-Spring-2026.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20260127T160000
DTEND;TZID=America/Los_Angeles:20260127T180000
DTSTAMP:20260512T162555Z
CREATED:20251201T230911Z
LAST-MODIFIED:20260512T162555Z
UID:54179-1769529600-1769536800@www.bio.uci.edu
SUMMARY:Dean's Distinguished Lecture - Winter 2026
DESCRIPTION:How Early-Life Experiences Shape Our Adult Behaviors\n\n\n\nJoin us for a talk with Dr. Tallie Z. Baram\n\n\n\n\n\n\n\nYou are invited to the Charlie Dunlop School of Biological Sciences’ Dean’s Distinguished Lecture Series\, featuring Tallie Z. Baram MD\, PhD on January 27\, 2026\, in the Crystal Cove Auditorium at the UCI Student Center. \n\n\n\nAlthough we do not remember events that happen to us during our first months and years\, these experiences shape our emotions and actions. Dr. Tallie Z. Baram will focus on how early-life experiences\, including stress\, are perceived by our brains\, and how these transient events can have enduring influence on our mental health.   \n\n\n\n\n\n\nEvent Details:\n\n\n\nTalk and Q&A: 4 to 5 p.m. \n\n\n\nReception: 5 to 6 p.m. \n\n\n\n\n\n\n\n\n\n\nAbout the Speaker:\n\n\n\n\nTallie Z. Baram MD\, PhDTallie Z. Baram MD\, PhD\, is the D. Shepard & Bren Distinguished Professor of Pediatrics\, Anatomy/Neurobiology and Neurology at UC-Irvine. Baram is best known for her pioneering and cutting-edge work on how adversity during sensitive developmental periods influences life-long cognitive and emotional health. Her group addresses these important questions at molecular\, cellular and circuit levels\, in both experimental animals and humans. Baram’s influential discoveries\, published in top journals\, have been cited ~40\,000 times and recognized by numerous awards. Baram is passionate and committed to mentoring\, and her former trainees\, from a broad range of backgrounds\, are now contributing independently to our understanding of the brain in health and disease.  \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nRegister to Attend the Dean’s Distinguished Lecture\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nThis event is free and open to the public. All are welcome to attend. If you have questions about this event\, please email biosci-events@uci.edu.
URL:https://www.bio.uci.edu/event/deans-distinguished-lecture-winter-2026/
LOCATION:Crystal Cove Auditorium – UCI Student Center\, 4113 Pereira Dr.\, Irvine\, California\, 92697\, United States
CATEGORIES:Dean's Distinguished Lecture,Dean's Office,Events
ATTACH;FMTTYPE=image/jpeg:https://www.bio.uci.edu/wp-content/uploads/2025/12/Thumbnail-DDL-Winter-2026.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250318T160000
DTEND;TZID=America/Los_Angeles:20250318T180000
DTSTAMP:20260826T212246Z
CREATED:20260826T212246Z
LAST-MODIFIED:20260826T212246Z
UID:50855-1742313600-1742320800@www.bio.uci.edu
SUMMARY:Dean's Distinguished Lecture - Winter 2025
DESCRIPTION:Using Neuroscience to Transform Our Understanding of DepressionJoin us for a talk with Diego Pizzagalli\, PhD\n\n\n\n\n\n \n\n\n\nYou are invited to the Charlie Dunlop School of Biological Sciences’ Dean’s Distinguished Lecture Series\, featuring Diego Pizzagalli\, PhD on March 18\, 2025\, in the Crystal Cove Auditorium at the UCI Student Center. \n\n\n\nDepression has become the leading cause of disability worldwide\, and its prevalence has increased substantially\, particularly among adolescents and young adults. Over the past decade\, there has been substantial progress in our understanding of possible causes of depression. In particular\, there have been breakthroughs in our ability to study the human brain that have allowed researchers and clinicians to identify individuals at increased risk for depression\, develop new treatments\, and identify biological markers that could be used to guide treatment. In this presentation\, Dr. Pizzagalli will summarize main risk factors for depression as well as examples of how findings in neuroscience have been harnessed to develop novel treatment approaches for this prevalent disorder. \n\n\n\n\n\n\n\n\n\n\n\n\nRegister to Attend the Dean’s Distinguished Lecture:\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nAbout Diego Pizzagalli\, PhD\n\n\n\n\n\n\n\nDr. Pizzagalli received his M.A. (1995) and Ph.D. (1998) from the University of Zurich\, Switzerland and did post-doctoral work at University of Wisconsin\, Madison. From 2002-2010 he was a faculty member in the Department of Psychology at Harvard University\, where he served as the John and Ruth Hazel Associate Professor of the Social Sciences. In 2010\, he was recruited to McLean Hospital to serve as the Founding Director of the Center for Depression\, Anxiety and Stress Research (CDASR)\, as well as the Director of the McLean Imaging Center (MIC). Until 12/2024\, Dr. Pizzagalli was a Professor of Psychiatry at Harvard Medical School\, and the Center Director for a Silvio O. Conte Center for Basic Translational Mental Health Research focused on the neurobiology of and novel treatment targets for depression and anxiety disorders. Since 2024\, he is also a Visiting Professor at the University of Oxford\, UK.  In 2025\, he joined the University of California at Irvine as the Founding Director of the Noel Drury\, M.D. Institute for Translational Depression Discoveries\, a Distinguished Professor in the Department of Psychiatry and Human Behavior and the Department of Neurobiology and Behavior\, and the Noel Drury MD Endowed Chair. \n\n\n\nClick to read more\nThe main goals of his research are to improve our understanding of the psychological\, environmental\, and neurobiological factors associated with mood disorders\, particularly major depression. To this end\, he integrates behavioral\, electrophysiological\, neuroimaging\, and\, more recently\, pharmacological approaches to investigate three putative endophenotypes of depression: anhedonia (loss of pleasure)\, increased stress sensitivity\, and executive function deficits. Dr. Pizzagalli has published over 360 papers and chapters and serves on the editorial board of 13 journals. He is the Editor-In-Chief for the journal Cognitive\, Affective and Behavioral Neuroscience. Among several awards\, he received the Distinguished Scientific Award for an Early Career Contribution to Psychophysiology from the Society for Psychophysiological Research (2006)\, the Early Career Award from the EEG and Clinical Neuroscience Society (2007)\, the Anne M. Cataldo Excellence in Mentoring Award from McLean Hospital (2015)\, two MERIT awards from the National Institute of Mental Health (2016\, 2022)\, The Stuart T. Hauser\, M.D. PhD. Mentorship Award in Psychiatry from Harvard Medical School (2017)\, the Joel Elkes Research Award from the American College of Neuropsychopharmacology (2017)\, a NARSAD Distinguished Investigator Award (2018)\, the Anna-Monika-Prize for Research in the Neurobiology and Treatment of Depressive Disorders (2019)\, the Gerald L. Klerman Senior Investigator Award from the Depression and Bipolar Support Alliance (2023)\, and the Christensen Fellowship from the University of Oxford (2024). Since 2019\, he has been a Highly Cited Researcher according to Web of Science. \n\n\n\n\n\n\n\n\n\n\n\n\nIf you have questions about this event\, please email biosci-events@uci.edu.
URL:https://www.bio.uci.edu/event/deans-distinguished-lecture-winter-2025/
LOCATION:Crystal Cove Auditorium – UCI Student Center\, 4113 Pereira Dr.\, Irvine\, California\, 92697\, United States
CATEGORIES:Dean's Distinguished Lecture,Events
ATTACH;FMTTYPE=image/png:https://www.bio.uci.edu/wp-content/uploads/2025/01/Diego-Pizzagalli-Featured-Image.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241023T160000
DTEND;TZID=America/Los_Angeles:20241023T180000
DTSTAMP:20260826T212319Z
CREATED:20260826T212319Z
LAST-MODIFIED:20260826T212319Z
UID:49873-1729699200-1729706400@www.bio.uci.edu
SUMMARY:Dean's Distinguished Lecture - Fall 2024
DESCRIPTION:Please arrive 15 minutes prior to the event for registration. Lecture from 4 to 5 p.mLight refreshments and beverages will be available during the reception from 5 to 6 p.m.  \n\n\n\n\n\n\n\nDefining the Mechanistic Basis of Neurodegenerative Proteinopathy:A 35 Year Genetic Odyssey\n\n\n\nJoin us for a talk with Distinguished Professor Albert La Spada\, M.D.\, Ph.D.\n\n\n\n\n\n\n\nYou are invited to the Charlie Dunlop School of Biological Sciences’ Dean’s Distinguished Lecture Series\, featuring Distinguished Professor Albert La Spada\, M.D.\, Ph.D.\, on October 23\, 2024\, in the Crystal Cove Auditorium at the UCI Student Center. \n\n\n\nEvent Details: \n\n\n\nTalk and Q&A: 4 to 5 p.m. \n\n\n\nReception: 5 to 6 p.m. \n\n\n\n\n\n\n\n\n\n\n\nRegister to Attend the Dean’s Distinguished Lecture\n\n\n\n\n\n\n\n\n\nAbout Distinguished Professor La Spada\n\n\n\nDistinguished Professor La Spada is a renowned researcher whose work focuses on understanding and treating neurodegenerative diseases such as Alzheimer’s\, Parkinson’s and ALS. His lab is working to uncover what causes nerve cells to break down and die\, using cutting-edge research to develop potential therapies for these devastating disorders. \n\n\n\nLearn more about the La Spada lab here. \n\n\n\nIf you have questions about this event\, please email biosci-events@uci.edu.
URL:https://www.bio.uci.edu/event/deans-distinguished-lecture-fall-2024/
LOCATION:Crystal Cove Auditorium – UCI Student Center\, 4113 Pereira Dr.\, Irvine\, California\, 92697\, United States
CATEGORIES:Dean's Distinguished Lecture
ATTACH;FMTTYPE=image/png:https://www.bio.uci.edu/wp-content/uploads/2024/09/DDL-Fall-2024-Featured-Image-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240410T160000
DTEND;TZID=America/Los_Angeles:20240410T180000
DTSTAMP:20260828T164256Z
CREATED:20260828T164256Z
LAST-MODIFIED:20260828T164256Z
UID:44850-1712764800-1712772000@www.bio.uci.edu
SUMMARY:Dean's Distinguished Lecture - Spring 2024
DESCRIPTION:Please arrive 15 minutes prior to the event for registration. Lecture from 4 to 5 p.mLight refreshments and beverages will be available during the reception from 5 to 6 p.m.  \n\n\n\n\n\n\n\nPrecious Birds and Flying Flowers:  The Sensory World of Butterflies\n\n\n\nThe mysterious beauty of butterflies has dazzled us from ancient times to modern. What makes them beautiful is partly in the eye of the beholder. Join us on a scientific tour of the role that visual senses play in ecosystems and the surprising sensory world inhabited by these enchanting insects. \n\n\n\n\n\n\n\nRegister to Attend the Dean’s Distinguished Lecture\n\n\n\n\n\n\n\n\n\nAbout Professor Briscoe\n\n\n\nBorn in Honolulu\, Hawaii\, Adriana D. Briscoe grew up in Colton\, California. She received a BA in Philosophy\, a BS in Biological Sciences\, and an MA in Philosophy from Stanford University and a PhD in Biology from Harvard University. She is a professor in the Department of Ecology and Evolutionary Biology at the University of California\, Irvine. Briscoe is known for studies of how color vision mediates ecological interactions between butterflies\, host plants\, and the environment\, in the context of mimicry and species recognition. Her discoveries have been featured on television and in museums both in the USA and in Europe. She has written and spoken about the importance of teachers in developing future scientists and the need for increased funding for Black\, Indigenous people of color (BIPOC) teacher training in science\, technology\, engineering\, and mathematics (STEM) in order to create a more just and diverse scientific workforce. She is leading the sequencing of California butterfly genomes for conservation purposes. \n\n\n\nBriscoe previously held a research fellowship at St. John’s College\, University of Cambridge\, U.K. She is an elected Fellow of the American Association for the Advancement of Science and the California Academy of Sciences\, and she was honored with the Distinguished Scientist Award from the Society for the Advancement of Chicanos/Hispanics and Native Americans in Science\, the first woman and third person overall to have been given all three of these awards. She is an elected member of the American Academy of Arts and Sciences. \n\n\n\nAuthor of numerous articles and book chapters\, Dr. Briscoe has delivered over 100 invited lectures. Her writing has appeared in The Conversation and LatinoRebels and in over 30 media outlets. \n\n\n\nLearn more about Professor Briscoe’s research here.
URL:https://www.bio.uci.edu/event/deans-distinguished-lecture-spring-2024/
LOCATION:Crystal Cove Auditorium – UCI Student Center\, 4113 Pereira Dr.\, Irvine\, California\, 92697\, United States
CATEGORIES:Dean's Distinguished Lecture
ATTACH;FMTTYPE=image/jpeg:https://www.bio.uci.edu/wp-content/uploads/2020/01/Adriana-Briscoe.jpg
ORGANIZER;CN="Dunlop School":MAILTO:biosci-events@uci.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240228T110000
DTEND;TZID=America/Los_Angeles:20240228T130000
DTSTAMP:20260826T212323Z
CREATED:20260826T212323Z
LAST-MODIFIED:20260826T212323Z
UID:44142-1709118000-1709125200@www.bio.uci.edu
SUMMARY:Winter 2024 - Dean's Distinguished Lecture
DESCRIPTION:Please arrive 15 minutes prior to the event for registration. Light lunch hors d’oeuvres and beverages will be available during the reception from 12 to 1 p.m. \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nDesigning Drugs for Human Diseases Using Structural Biology\n\n\n\n\n\n\n\nAbout the Lecture\n\n\n\nThis lecture will discuss how structural biology provides the required information for designing specific therapeutic agents and will present a few specific examples of potential drugs designed here at UCI targeting neurodegenerative diseases and melanoma. In addition\, included will be an example of a UCI industrial collaboration that led to important insights into how certain HIV antiviral drugs work. \n\n\n\nRead more about lecture…\nA majority of drugs are targeted to specific proteins. Proteins are large complex molecules consisting of thousands of atoms while most drugs are much smaller consisting on the order of dozens of atoms. Enzymes\, the engines of life that catalyze all chemical transformations in biology\, are proteins that form highly ordered three-dimensional structures. One region of the structure that carries out the required transformations is called the active site. Binding of a drug to the active site can prevent the enzyme from carrying out its normal function. For example\, certain antibiotics bind to bacterial enzyme active sites to block their activity thereby preventing infection or growth/proliferation. Knowing the detailed three-dimensional structure of the protein can greatly streamline the process of designing novel drugs that specifically bind to the active site.  \n\n\n\n\n\n\n\n\n\n\n\n\nRegister to Attend\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nAbout Distinguished Professor Thomas Poulos\n\n\n\nThomas Poulos PhD is a Distinguished Professor of Molecular Biology and Biochemistry at the University of California\, Irvine. He has had an illustrious career in both the private sector and academia \n\n\n\nClick here to read more about Professor Poulos background…\nDuring his graduate years (1968-1972) in the Dept. of Biology at UCSD Prof. Poulos studied nuclease mechanisms in the lab of Prof. Paul Price. Realizing that to understand enzyme function\, one must know structure\, he moved to Joe Kraut’s lab in the Dept. of Chemistry at UCSD to learn protein crystallography. Prof. Poulos first studied transition state analogs bound to the serine protease\, subtilisin. He then solved the first heme enzyme structure\, cytochrome c peroxidase\, and initiated the early work on cytochrome P450cam. During this time he secured NSF support for both the CCP and P450 work. In 1983 Prof. Poulos was recruited by Genex Corp.\, a relatively new biotechnology company in Maryland. He first held the title of Principal Research Scientist and in 1985 became the Director of Protein Engineering. During this period Genex solved the structure of some industrially important enzymes\, developed proteases of enhanced stability that have been used commercially\, and developed what has come to be called single-chain antibodies. The structure of the first P450 (supported by NIH) was solved during this period. After 4 years at Genex\, Prof. Poulos returned to academia and in 1987 he accepted the position of Director and Professor of Chemistry at the University of Maryland’s Center for Advanced Research in Biotechnology or CARB. CARB started with a small administrative staff of 3 and one technician. Over the next 4 years Prof. Poulos oversaw the development of CARB to a total staff of 60 including University of Maryland faculty and faculty from the National Institute of Science and Technology\, the University’s partner in the development of CARB. In 1991 he received the Presidential Meritorious Service Award from the University of Maryland.In 1992 Prof. Poulos moved to UCI where he initiated work on nitric oxide synthase which\, in collaboration with Prof. Richard Silverman at Northwestern\, has led to the development of the most potent isoform-selective inhibitors of neuronal nitric oxide synthase inhibitors yet developed. These inhibitors exhibit exceptional in vivo neuroprotection in animal model systems. In 2004 he won the Brodie Award in drug metabolism from the American Association of Pharmacology and Experimental Therapeutics and 2014 the Gordon Hammes American Chemical Society Biochemistry Lectureship and has given several named lectures. Prof. Poulos has served as a member and Chair of various NIH and NSF review panels and served on the NCI Board of Scientific Counselors. He has held various leadership positions including Director of the Program in Pharmaceutical Sciences\, Director of the Irvine Research Unit in Structural Biology\, and Co-Director of the Chemical and Structural Biology Program in the Chao Family Comprehensive Cancer Center. He currently serves on the Stanford Synchrotron Radiation Lab Advisory Committee. As of Feb. 2021\, Prof. Poulos has published over 300 papers/reviews.
URL:https://www.bio.uci.edu/event/winter-2024-deans-distinguished-lecture/
LOCATION:Crystal Cove Auditorium – UCI Student Center\, 4113 Pereira Dr.\, Irvine\, California\, 92697\, United States
CATEGORIES:Dean's Distinguished Lecture
ATTACH;FMTTYPE=image/jpeg:https://www.bio.uci.edu/wp-content/uploads/2020/01/poulos_head.jpg
ORGANIZER;CN="Dunlop School":MAILTO:biosci-events@uci.edu
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DTSTART;TZID=America/Los_Angeles:20231012T160000
DTEND;TZID=America/Los_Angeles:20231012T180000
DTSTAMP:20260828T163254Z
CREATED:20230927T163422Z
LAST-MODIFIED:20260828T163254Z
UID:43452-1697126400-1697133600@www.bio.uci.edu
SUMMARY:Dean's Distinguished Lecture Series - Fall 2023
DESCRIPTION:Join us on Thursday\, October 12 from 4 to 6 p.m. at the Crystal Cove Auditorium for our next Dean’s Distinguished Lecture with Professor Aimee Edinger\, VMD/PhD. \n\n\n\nDescription:\n\n\n\nThe Edinger laboratory practices “translational cell biology\,” studying the flow of traffic on cellular highways with an eye to developing new medicines that can be used to treat lethal human diseases. This lecture will describe how natural compounds found in yeast and humans might be leveraged to set up roadblocks that kill drug-resistant tumor cells\, tame the obesity epidemic\, and help deliver next-generation DNA and RNA medicines. \n\n\n\n\nAbout the Speaker\n\n\n\nDr. Edinger’s journey began in San Diego with a childhood dream of becoming a veterinarian. This goal took her to UC Davis\, where she engaged in undergraduate research and was soon captivated by the allure of scientific inquiry. Her fascination with research led her to pursue a dual veterinary/PhD program at the University of Pennsylvania. There\, she pecialized in both large and small animal medicine and completed a PhD thesis focused on HIV vaccine development. After deciding to pursue academic research\, Dr. Edinger undertook postdoctoral training in cancer biology in the esteemed lab of Craig Thompson at PENN. Throughout her nearly two decades at UCI\, Dr. Edinger has garnered recognition for her unwavering dedication to teaching and mentorship\, as well as for her groundbreaking research initiatives. Beyond her academic accolades\, she has displayed her innovative prowess by being named an inventor on seven patents. Furthermore\, she has worked to translate her scientific breakthroughs into tangible impact by founding a company to develop novel pharmaceuticals from the discoveries originating in her laboratory. \n\n\n\n> Learn More About Dr. Edinger \n\n\n\n\n\n\n\n\nRegister to Attend
URL:https://www.bio.uci.edu/event/deans-distinguished-lecture-series-fall-2023/
LOCATION:Crystal Cove Auditorium\, UCI Student Center\, CA\, United States
CATEGORIES:Dean's Distinguished Lecture
ATTACH;FMTTYPE=image/png:https://www.bio.uci.edu/wp-content/uploads/2023/09/aimee.png
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221115T160000
DTEND;TZID=America/Los_Angeles:20221115T173000
DTSTAMP:20260828T164158Z
CREATED:20260828T164158Z
LAST-MODIFIED:20260828T164158Z
UID:39580-1668528000-1668533400@www.bio.uci.edu
SUMMARY:Dean's Distinguished Lecture - Fall 2022
DESCRIPTION:About the Lecture \n\n\n\nAlzheimer’s disease is a major health crisis that is projected to become an even larger threat in the coming decades. According to the National Institute on Aging\, the number of Americans 65 and older with Alzheimer’s could rise from 5.8 million in 2020 to 13.8 million by 2050. Given the severity of this health crisis and the toll it takes on patients\, their families and society\, we must be prepared today to address the needs of tomorrow. \n\n\n\nDean Frank LaFerla will present an overview of the state of Alzheimer’s disease research. Following his presentation\, the panel will cover emerging trends in research\, care and the upcoming challenges we will face and how we might mitigate them. \n\n\n\nTuesday\,November 15\, 20224:00 PM – 5:30 PM \n\n\n\nThe Beckman Center100 AcademyIrvine\, CA 92617 \n\n\n\nAbout the Panel \n\n\n\nThe discussion panel will be comprised of a group of esteemed biologists\, researchers and community leaders. \n\n\n\nFrank LaFerla\, PhDDean and Chancellor’s Professor\, Department of Neurobiology and Behavior \n\n\n\nJoshua Grill\, PhDDirector\, UCI Institute for Memory Impairments and Neurological Disorders (UCI MIND); Professor\, Department of Neurobiology & Behavior and Psychiatry & Human Behavior \n\n\n\nElizabeth Head\, PhDProfessor and Vice Chair for Research\, Department of Pathology & Laboratory Medicine \n\n\n\nDavid Sultzer\, MDClinical Research Director\, UCI MIND; Professor\, Department of Psychiatry & Human Behavior \n\n\n\nDeborah LevyExecutive Director\, Alzheimer’s Association Orange County Chapter \n\n\n\nQ&A with audience will follow panel discussion. Following the lecture and panel discussion\, attendees are invited to view a special presentation featuring real brain tissue. \n\n\n\nRSVP \n\n\n\nWe invite you to join us on Tuesday\, Nov. 15 to hear from Alzheimer’s disease experts as they discuss the latest in Alzheimer’s research\, treatment and management. Dean LaFerla will moderate the discussion. \n\n\n\nSpace is limited. Please RSVP at your earliest convenience to reserve your spot. The Beckman Center also requires that guest are vaccinated against COVID-19.  \n\n\nOops! We could not locate your form. \n\n\n\nIf you have any questions\, please email us at biosci-events@uci.edu.
URL:https://www.bio.uci.edu/event/deans-distinguished-lecture-looking-to-a-future-without-alzheimers/
LOCATION:The Beckman Center\, 100 Academy\, Irvine\, 92617\, United States
CATEGORIES:Dean's Distinguished Lecture
ATTACH;FMTTYPE=image/png:https://www.bio.uci.edu/wp-content/uploads/2022/10/alzheimers.png
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20211102T160000
DTEND;TZID=America/Los_Angeles:20211102T191500
DTSTAMP:20260828T164040Z
CREATED:20260828T164040Z
LAST-MODIFIED:20260828T164040Z
UID:35801-1635868800-1635880500@www.bio.uci.edu
SUMMARY:Dean's Distinguished Lecture: Picture a Scientist
DESCRIPTION:About the Event:\n\n\n\nThis Special Dean’s Distinguished Lecture will host a film screening and panel discussion of “Picture a Scientist”. It is a feature length documentary chronicling the researchers who reveal their own experiences with gender and race discrimination with the goal of enhancing awareness of gender bias and revolutionizing the culture of science. The film challenges audiences of all backgrounds and genders to question their own implicit biases and consider how to change them. \n\n\n\nPanelists\n\n\n\nDunlop School panelists who will lead the discussion after the film: \n\n\n\nAgenda\n\n\n\n4:00 PM – Welcome; screening of the film Picture a Scientist \n\n\n\n5:40 PM – Panel discussion with audience participation \n\n\n\n6:15 PM –  One hour Reception in lobby. Light appetizers and refreshments will be served. \n\n\n\nRegister Today! \n\n\n\nFind resources for OEOD and Title IX Office:  www.bio.uci.edu/picture-a-scientist/resources
URL:https://www.bio.uci.edu/event/ddl-picture-a-scientist/
LOCATION:California
CATEGORIES:Dean's Distinguished Lecture
ATTACH;FMTTYPE=image/png:https://www.bio.uci.edu/wp-content/uploads/2018/07/picture-a-scientist-image-cropped-trans.png
ORGANIZER;CN="UC Irvine Charlie Dunlop School of Biological Sciences":MAILTO:biosci-events@uci.edu
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210204T160000
DTEND;TZID=America/Los_Angeles:20210204T173000
DTSTAMP:20260826T212323Z
CREATED:20260826T212323Z
LAST-MODIFIED:20260826T212323Z
UID:34075-1612454400-1612459800@www.bio.uci.edu
SUMMARY:COVID 19 – Moving Beyond the Pandemic
DESCRIPTION:COVID 19 – Moving Beyond the Pandemic\n\n\n\nA Discussion on Research\, New Strains\, Testing\, Neurological Challenges and Vaccines\n\n\n\nThis event has passed. Registration is closed. \n\n\n\nAbout the Panel\n\n\n\nThe discussion panel will be comprised of a group of esteemed biologists\, researchers and scholars. Q&A with audience will follow presentations. \n\n\n\nMichael J. Buchmeier\, PhD\n\n\n\nAssociate Director\, Center for Virus Research; Professor\, Department of Molecular Biology and Biochemistry; Division of Infectious Disease\, Department of Medicine; Department of Microbiology and Molecular Genetics \n\n\n\nAbout Prof. Buchmeier’s Research \n\n\n\nProfessor Buchmeier’s laboratory investigates the pathogenesis and control of viral infections. His focus is primarily on two classes of RNA viruses that affect the central nervous system (CNS): the murine and human coronaviruses and arenaviruses. The laboratory team studies the structure\, function and contribution of encoded proteins to the viral life cycle and the relationship to disease. The Buchmeier lab is also engaged in studies on antiviral drug design and investigating how viruses interact with hosts during acute and persistent infection. \n\n\n\nIlhem Messaoudi\, PhD\n\n\n\nDirector\, Center for Virus Research; Professor\, Department of Molecular Biology and Biochemistry \n\n\n\nAbout Prof. Messaoudi’s Research \n\n\n\nResearch activities in the Messaoudi laboratory are focused on the following areas; 1) impact of advanced age on immune fitness and ability to respond to infection; 2) modulation of immune function by alcohol use disorder and obesity; 4) maternal-fetal health; and 3) mechanisms of viral pathogenesis. Under the fourth goal\, the Messaoudi team has begun investigating how age and other co-morbidities impact immunity and COVID-19 severity. Additionally\, the team is carrying out several surveillance projects at UCI and the community to understand disease spread and prevalence. \n\n\n\nJohn Gerace\n\n\n\nPresident\, DiaSorin Molecular LLC; UCI School of Biological Science’s Dean’s Leadership Council \n\n\n\nAbout Mr. Gerace and DiaSorin Molecular \n\n\n\nJohn Gerace has spent his career working at some of the nation’s top biotechnology companies. He co-founded Calabri Biosciences – a biosensor / digital health technologies investment portfolio\, and in 2017\, was appointed President of DiaSorin Molecular LLC. DiaSorin Molecular is a laboratory diagnostics company that specializes in the immunodiagnostics and molecular diagnostics segments. They manufacture and distribute molecular diagnostic products to hospitals and reference laboratories. Under the leadership of Mr. Gerace\, DiaSorin Molecular has created the Simplexa COVID-19 Direct kit\, which has been used to detect the SARS-CoV-2 virus from nasal swab\, nasopharyngeal swab\, nasal wash/aspirate and BAL specimens in Orange County hospitals and beyond. \n\n\n\nAndrew Noymer\, PhD\n\n\n\nAssociate Professor\, Department of Population Health and Disease Prevention; Public Health \n\n\n\nAbout Prof. Noymer’s Research \n\n\n\nAndrew Noymer is a medical demographer and epidemiologist specializing in studying mortality from infectious diseases at the population level.  His work has focused on pandemics\, most notably the 1918 influenza pandemic\, which is the historical example closest to the current Covid crisis.  Additional recent work has included excess mortality estimation of influenza deaths using negative binomial models.  During the current pandemic\, Professor Noymer has played a role in helping the public understand the epidemiologic and societal trends and has been quoted in local\, state\, national\, and international print\, radio and television media.  For this work\, he was named to the Orange County Register’s 100 most influential people in 2020. He has also worked on several related topics\, including mathematical models of rumor transmission and methodological problems in population studies\, such as introducing a formal convex hull approach to the field \n\n\n\nThomas E. Lane\, PhD\n\n\n\nChancellor’s Professor\, Department of Neurobiology and Behavior; Center for Virus Research; Institute for ImmunologyAbout Prof. Lane’s Research \n\n\n\nThe Lane laboratory has over 20 years of experience investigating the events that initiate and maintain inflammation within the central nervous system (CNS) following coronavirus infection. In response to the COVID-19 pandemic\, the lab began exploring the consequence of SARS-CoV-2 infection focusing on neuroinflammation\, neuropathology and functional deficits. With this in mind\, the Lane lab uses animal models to evaluate the ability of the virus to enter the CNS following intranasal inoculation and identify cell types that are infected and capable of replicating the virus. More specifically\, the laboratory is identifying the functional roles of microglia (the “immune cell” of the CNS) in contributing to both host defense and disease following SARS-CoV-2 infection. Finally\, the team also utilizes human brain organoids and cell culture models to assess the ability of SARS-CoV-2 to infect\, replicate and trigger an immune response in CNS cells. \n\n\n\nFrank M. LaFerla\, PhD\n\n\n\nModerator; Dean and Chancellor’s ProfessorAbout Dean LaFerla’s Research \n\n\n\nFrank LaFerla is a Chancellor’s Professor of neurobiology and behavior and the dean of the UC Irvine Charlie Dunlop School of Biological Sciences. He is also the director of the National Institutes of Health (NIH)-funded UCI Alzheimer’s Disease Research Center and co-director of NIH-funded MODEL-AD at UCI\, a research effort to develop the next generation of model organisms to evaluate and cure Alzheimer’s disease. Dean LaFerla’s laboratory focuses on understanding the pathogenesis of Alzheimer’s Disease\, the most common form of dementia. His research has had a global influence on the field. Some of the model organisms he has generated have been distributed to over 150 researchers in more than 20 countries worldwide \n\n\n\nAbout the Lecture\n\n\n\nWe are living in the time of COVID-19\, a disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For almost a year\, we’ve witnessed the relentless spread of the disease as it affected young and old around the world. Our health\, our families\, our homes\, our lives\, our economy\, our very way of life – all turned upside down. \n\n\n\nNow\, there is light at the end of a very dark tunnel. \n\n\n\nWe invite you to join us on Thursday\, Feb. 4 to hear from researchers at UCI’s School of Biological Sciences and of Public Health and from DiaSorin Molecular LLC as they discuss developments in their areas of expertise and findings in the battle against COVID-19. John Gerace of DiaSorin will talk about the challenges of delivering and testing for COVID-19\, how they overcame those challenges\, and what that means for the public. Professor Noymer will discuss population health\, epidemiology and the impact of vaccines. Professor Lane will review the neurological aspects of the disease\, and Professor Buchmeier will cover the origin and evolution of coronaviruses and what that means to humanity. Additionally\, Professor Messaoudi will share immunological insights about the SARS-CoV-2 virus and vaccines. Dunlop School’s Dean Frank LaFerla will moderate the discussion. \n\n\n\nAudience members will then have the opportunity to ask the panel questions during the Q&A session \n\n\n\nThis event will be a virtual webinar. Pre-registration is required.A Zoom link will be provided to confirmed registrants via email the morning of the event. \n\n\n\nLearn More About the Dean’s Distinguished Lecture Series
URL:https://www.bio.uci.edu/event/ddl_2-4-21/
LOCATION:Zoom
CATEGORIES:Dean's Distinguished Lecture
ATTACH;FMTTYPE=image/png:https://www.bio.uci.edu/wp-content/uploads/2020/10/ddl-cover-image.png
ORGANIZER;CN="UC Irvine Charlie Dunlop School of Biological Sciences":MAILTO:biosci-events@uci.edu
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