A postdoctoral position is available in the laboratory of Dr. Irina Sevrioukova in the Department of Molecular Biology and Biochemistry in the School of Biological Sciences at the University of California, Irvine. The current project is to study structure/function relationships and the mechanism of ligand binding and allosteric regulation of drug-metabolizing enzymes, particularly human CYP3A4 and CYP3A7, using a combination of biochemical, biophysical and structural approaches.

The ideal candidate should be self-motivated, with a PhD degree in life sciences and training in recombinant enzyme expression, purification and functional characterization. Other requirements include 1) publications in peer-reviewed journals, 2) strong organizational, written and oral communication skills, and 3) willingness to learn new approaches. Prior experience with CYPs and the knowledge of analytical mass spectrometry methods, chemical labeling and protein crystallography would be beneficial but not strictly required.

For more information about this position, contact Dr. Sevrioukova at sevrioui@uci.edu.

Qualified candidates should submit their curriculum vitae, cover letter (a brief statement of research accomplishments and interests) and the names and contact information of three references to the following on-line recruitment URL:


Applications will be considered until position is filled.

UCI provides excellent support for postdocs (https://grad.uci.edu/postdocs/information-for-postdocs/), which includes the development of leadership and teaching skills, career development, and full benefits. Several childcare services are available on campus. UCI campus is located at a driving distance to Los
Angeles and San Diego, and 15 minutes away from the ocean. The city of Irvine is recognized as one of the greenest, safest and happiest places to live in America (https://urldefense.com/v3/https://www.cityofirvine.org/2021-2018 awards;!!CzAuKJ42GuquVTTmVmPViYEvSg!I9TEqolcHfJRi_
vxnyvuhDL1oNmQxBxexTkMffp7OZZWmdb6ixm3VBicosz2T2ykB5V6xWekgou-QIrMA$ ).”

Basic qualifications (required at time of application)
Accepting all applicants.

Document requirements
Curriculum Vitae – Your most recently updated C.V.
Cover Letter
Statement of Research (Optional)
Misc / Additional (Optional)
Reference requirements
3-5 required (contact information only)
Apply link: https://recruit.ap.uci.edu/JPF07546
Postdoctoral Scholar- Sevrioukova Lab (JPF07546)

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.