The Department of Molecular Biology and Biochemistry in the School of Biological Sciences is accepting applications in the area protein biochemistry / structural biology related to Alzheimer’s disease. The person in the position will perform experiments with human brain samples and transgenic mice under the direction of Dr. Charles Glabe. This NIH-funded project the protein composition and structures of amyloid aggregates that are deposited at different times and locations in distinct subtypes of disease. The hypothesis to be examined is that different types of amyloid accumulate in different phenotypic variants of disease. person also will work on the seeded aggregation and replication of these amyloids isolated from human brain. Renewal of the appointment will be contingent on the availability of adequate funding and performance.
The University of California, Irvine is ranked among the nation’s best research institutes with over $90,000,000 in current funding. Enrichment opportunities abound through the Alzheimer’s Disease Research Center, the Memory Impairment and Neurodegenerative Disease Institute and the Center for the Neurobiology of Learning and Memory. Irvine has a pleasant climate, five miles from the beach.
Ph.D. in biochemistry, cell biology or biophysics with experience in protein biochemistry is required. Experience working with insoluble proteins and amyloids and proteomic analysis are preferred. Experience with cryo-EM or solid state NMR is also desirable.
Candidate demonstrates significant, original, and creative contribution to a research or creative program or project, demonstrates professional competency and activity of high quality and significance, performing university and public service is encouraged.
Qualified candidates should submit their curriculum vitae, a cover letter, and the names and contact information of three references to the following on-line recruitment URL:
The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.