Professor Arthur Lander, M.D., Ph.D. is a Donald Bren Professor in the department of Developmental and Cell Biology, and the director of the Center for Complex Biological Systems. Professor Anne Calof, Ph.D. is a professor in the departments of Anatomy and Neurobiology, and Developmental and Cell Biology. Together with Professor Qing Nie in the department of Mathematics, Professors Lander and Calof received a new RO1 grant entitled, “Spatial Dynamics of Tissue and Organ Size Control”, funded by the National Institute of Neurological Disorders and Stroke. Their research will utilize mathematical modeling and experimental genetically engineered mice to investigate how the size of tissues and organs are precisely specified in the face of developmental variability and external perturbations. The results from their study will help to understand the origins of birth defects and the mechanisms underlying altered growth following disease and injury. The $2.1 million grant is for a funding period of five years.