November 13 @ 11:00 AM – 12:00 PM
Dr. Xing Dai
Professor, SOM – Biological Chemistry
University of California, Irvine
“Beauty is Skin Deep: Epithelial Stem Cell Plasticity, Immune Crosstalk, and Metabolism”
Abstract: Skin is a dynamic organ that relies on the proper regulation of adhesive properties and metabolic activities of epithelial stem and progenitor cells for optimal development, homeostasis, and regeneration. I will summarize our work on transcription factors that modulate epithelial-mesenchymal plasticity and how they coordinate epithelial fate with stem cell function. Additionally, I will discuss our findings on how skin epithelial stem and progenitor cells interact with immune cells to regulate inflammation. Finally, I will present our recent research on the role of amino acid metabolism in controlling the proliferation and differentiation of skin epithelial stem and progenitor cells.
Seminar will be held in person only.
For questions about this event, please contact Mayra Rubio at mrubio3@uci.edu.