When cells are stressed by aging, infection or environmental damage, they can release fragments of their own DNA into the cell interior. This misplaced DNA acts like an alarm, triggering inflammation meant to protect the body. But when that response goes unchecked, it...
Cancer is one of the world’s most pressing health challenges, and despite decades of progress, many treatments still come with harsh side effects that can harm healthy cells along with tumors. A major reason for this is that current drugs often target the basic...
Associate Professor Vivek Swarup of the UC Irvine Charlie Dunlop School of Biological Sciences has been awarded a competitive Alzheimer’s Association Research Grant to investigate an emerging area of study in Alzheimer’s disease: the role of oligodendrocytes....
Jordan Woytash, first auther Olga Razorenova, PI Triple-negative breast cancer (TNBC) is one of the most aggressive and difficult-to-treat forms of breast cancer. Unlike other breast cancer subtypes, TNBC lacks the three key receptors — estrogen, progesterone and HER2...
From left: Assistant Professor Benjamin Morehouse, undergraduate Anny Wang, graduate student Eirene Marie Ednacot. Irvine, Calif., August 6, 2025 — In a new study published in Science, researchers from the Charlie Dunlop School of Biological Sciences at UC Irvine, in...
The UC Irvine Charlie Dunlop School of Biological Sciences is proud to announce that seven of its faculty members have been selected as 2024 awardees of the UC Irvine Anti-Cancer Challenge, a community-based initiative that raises funds to support promising cancer...
Assistant Professor Evgeny Kvon and graduate student Grace Bower. Irvine, Calif., July 2, 2025 — How do cells know which genes to activate, and when? For decades, scientists have puzzled over how distant parts of our DNA — sometimes millions of base pairs apart — can...
Ghazaleh Eskandari-Sedighi, PhD, a postdoctoral research fellow at the University of California, Irvine, has been awarded a prestigious research grant from the BrightFocus Foundation’s Alzheimer’s Disease Research program. The two-year, $200,000 grant will support her...
Each spring, UC Irvine’s campus comes alive with ideas, energy and discovery as undergraduate researchers take the spotlight. During April and May, the UC Irvine Charlie Dunlop School of Biological Sciences hosts research presentations that are the culmination of its...
Professor Diego A. Pizzagalli is lead investigator for this study.