New Study Identifies Anti-Cancer Effect of Statins

Molecular Biology and Biochemistry Professor David Fruman has published a new manuscript in the journal Science Translational Medicine. In the paper, Professor Fruman and colleagues identify an alternative anti-cancer benefit of statins- drugs normally prescribed for treating high cholesterol. Statins had previously been known to block a cellular pathway that many cancers use to potentiate … Read More […]

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Macro Push to Understand Micro Life Forms

Microorganism communities like bacteria and fungi are complex and diverse and inhabit earth’s many environments, from the human body to oceans and soils. Our bodies contain thousands of bacterial species. Soil contains tens of thousands of bacterial and fungal species. A liter of seawater contains a billion viruses. This diversity is central to both human … Read More […]

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Smaller, Faster, Stronger

In new research published in the journal, Science, Professor Manny Azizi and his colleagues, Sarah Bergbreiter (University of Maryland) and S.N. Patek (Duke University), describe a new mathematical model to help understand how small organisms generate amplifying mechanisms that allow them to jump, strike and react with great power and speed. The team sought to … Read More […]

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PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells

Aimee Edinger Associate Professor Developmental and Cell Biology Successful tumor cells must develop strategies to grow even in the face of famine. Tumors do not have enough blood vessels to keep all the cancer cells well fed, and the blood vessels that are present are leaky and don’t function properly. Despite these supply-side limitations, tumor … Read More […]

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Mentoring Helps Build Biologists of Tomorrow

Many of science’s most exciting and relevant advances are taking place in the field of biology. And with good reason. Biological solutions are needed to overcome the global challenges we face that affect our health, our economy, our society and our world every day. To help students prepare for successful futures in such a demanding … Read More […]

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Donuts with the Dean Mixes Students and Executives

For students, faculty and staff hungry for a snack and some new knowledge, Donuts with the Dean offers just the right mix. The quarterly program was established by Dean LaFerla to provide an opportunity for direct interaction between students and the dean as well as invited faculty/staff. The dean also extends an invitation to a … Read More […]

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Gift Honors Professor James McGaugh and Funds Award

Dr. James T. Goodrich has led a highly successful career as a world-leading neurosurgeon. He is currently Professor of Neurological Surgery, Pediatrics and Plastic and Reconstructive Surgery as well as Chief of the Division of Pediatric Neurosurgery at the Albert Einstein College of Medicine in New York City, working at the Children’s Hospital at Montefiore … Read More […]

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New Genetically Engineered Mouse Models Could Boost Alzheimer’s Drug Research

UCI researchers, lead by Biological Sciences School Dean Frank LaFerla and Professor Andrea Tenner, have received an $11.4 million grant from the National Institute on Aging to create several humanized mouse models to more accurately mimic human Alzheimer’s conditions, and serve as valuable tools to better understand and target Alzheimer’s pathology. Biological Sciences School Professors … Read More […]

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Faculty Spotlight – Raju Metherate, Ph.D.

Professor Raju Metherate is a neuroscientist in the Department of Neurobiology and Behavior (NBB), and is the new Associate Dean for Undergraduate Education for the School of Biological Sciences at UCI. Professor Metherate, a faculty member at UCI for over two decades, has focused his research on understanding the workings of the auditory cortex. His … Read More […]

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Staff Spotlight – Yergalem T. Meharenna, Ph.D.

In her role as Training Grant Officer, Yergalem (Yerga) Meharenna balances her commitments to the UCI Schools of Biological Sciences and Medicine, coordinating training efforts that entail collaboration across the two Schools. Yerga received her Ph.D. in Genetic Engineering from Imperial College London in 2000. After completing her thesis, she came to work as a … Read More […]

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