Building and keeping muscle is essential for lifelong health, not just athletic performance. Strong skeletal muscle supports mobility, healthy aging and recovery after injury or illness.
UC Irvine Researchers Uncover Key Genetic Clues Behind Alzheimer’s and Pick’s Diseases
Associate Professor Vivek Swarup, postdoctoral scholar Sudeshna Das, and PhD Candidate Zechuan Shi. Irvine, Calif., November 12, 2025 — Scientists at the UC Irvine Charlie Dunlop School of Biological Sciences have uncovered how subtle changes in gene regulation may...
UCI Scientists Help Uncover a New Bacterial Defense System Against Viruses
Morehouse lab: left to right back: Ali Nabhani, David Dinh, Benjamin Morehouse, Daniel Izrailevsky; left to right front: Eirene Marie Ednacot, Christy Nguyen Whiteley lab: Front row (L->R): Ashley Sullivan, Toni Nagy, Laurel Robbins; Back row (L->R): Aaron...
UC Irvine Study Identifies Overlooked Immune Cell Pathway Into the Brain
CCR2+ (red, monocytes) cells enter the brain parenchyma from the velum interpositum (blue, laminin). CX3CR1+ cells (green) represent resident macrophages or microglia. Photo credit: Rocio Barahona, Lindsay Hohsfield, and Kim Green. Irvine, Calif., June 3, 2025 —...
UC Irvine Researchers Explore Promising New Pathway for Treating Inflammatory Diseases
Irvine, Calif., May 15, 2025 — Inflammatory diseases such as arthritis, Alzheimer’s and even certain rare genetic disorders affect millions worldwide and often have few effective treatment options. A new study from the lab of Assistant Professor Reginald McNulty at...
Large, highly likely rewards can increase motivation in individuals who have recovered from depression
Professor Diego A. Pizzagalli is lead investigator for this study.
Study Finds Brain-Based Markers Could Help Personalize Depression Treatment
Diego Pizzagalli, PhD, director of the Noel Drury, M.D. Institute for Translational Depression Discoveries, and Peter Zhukovsky, PhD, Scientist in the Brain Health Imaging Centre at the Centre for Addiction and Mental Health. Irvine, Calif., April 23, 2025 — Finding...
Engineered microglia show promise for treating Alzheimer’s, other brain diseases
UC Irvine Team Maps Viral Spread in the Gut Microbiome at Single-Particle Resolution
Postdoctoral scholar Liz Ortiz and Assistant Professor Travis Wiles track the movement of phages by tagging them with fluorescent markers. Photo credit: Ritwik Kumar. Irvine, Calif., April 18, 2025 — In a world where gut health is increasingly linked to everything...
The Hidden Architects of Evolution How “Jumping Genes” Shape Genetic Diversity
Lee Lab team. From left: Zita Gao (second author), Kayla Ly (third author), Grace Lee, Yuheng Huang (first author). Irvine, Calif., March 24, 2025 — Why do genetic recombination rates — the process that reshuffles DNA during reproduction — vary so widely between...